ʻO ka mea i hala koke iho nei, ua paʻi nā hui nui paka nui ʻelua, ʻo PMI a me BAT, i nā pepa noiʻi ma nā nūpepa olakino kiʻekiʻe.ʻO nā hopena o ka noiʻi e hōʻike ana i nā huahana paka hou e like me ka e-cigarettes a me ka wela-not-burn ʻaʻole i hōʻino a ʻona ma mua o ka paka kahiko, a hiki ke hoʻemi nui i ka hopena i ka ʻōnaehana hanu.poino.
Ke hoʻonui nei ka ʻike o ka poʻe i ka pōʻino o ka puhi paka, ʻike nui ʻia ka e-cigarette e ka lehulehu ma ke ʻano he pani no ka paka.Eia naʻe, ka hopena lōʻihi o ka mea ʻonopaka uilaʻO nā hui ʻono a me ka uahi paka ma luna o ka poʻe puhi paka ke ʻimi hou ʻia.
I kēia mau lā, ua paʻi ʻo PMI Philip Morris International i kahi hōʻike noiʻi "Assessment of inhalation toxicity o ka uahi paka a me nā aerosol mai nā hui ʻono: 5-week study in A/J mice" ma ka British Journal of Toxicology "Journal of Applied Toxicolog", e wehewehe ana i nā kikoʻī. o nā kumuhana pili Nā ʻanuʻu noiʻi a me nā hopena.
Ma ka hoʻokolohua, 87 kane iole a me 174 nulliparous a hapai wahine iole i randomly haawiia i 9 hoʻokolohua pūʻulu, a alakaʻi 'ia i loko o ka lewa, paka paka, a me e-cigarette aerosols me ekolu okoa concentrations o flavorants, kiʻekiʻe, waena, a me ka haʻahaʻa.ʻO ka hōʻike ʻana a hiki i 6 mau hola i ka lā, 5 mau lā i kēlā me kēia pule, no 5 mau pule i ukali ʻia e ka necropsy, ke kaumaha o ke kino a me ka loiloi histopathological.
Hōʻike ke kiʻi i ka ʻikepili loiloi o ka mumū o ka ʻiole.Hiki ke ʻike ʻia ʻo ka ʻikepili kūpono o nā ʻiole i ʻike ʻia i ka uahi paka ka pane ʻike loa (ʻāpana ʻulaʻula)
Ua hōʻike ʻia nā hopena hōʻike hope loa i ka wā i hōʻike ʻia ai nā ʻiole i nā aerosol e-cigarette me nā mea ʻono a me nā mea ʻono ʻole, ke hoʻohālikelike ʻia me ka poʻe i ʻike ʻia i ka uahi paka, ʻaʻohe loli nui i ka ʻōpū hanu, ka ihu, a me ka laryngeal epithelial tissues. ʻAʻole hoʻonāukiuki ka sol i nā ʻiʻo a me nā ʻāpana pili.Ua hōʻoia hou nā hopena hoʻokolohua, i hoʻohālikelike ʻia me nā paka kuʻuna,nā paka uilahiki ke hōʻemi nui i ka ʻāʻī o ka māmā, a me ka pōʻino i ka ihu, ka ʻāʻī a me ka epithelium tracheal.
Ua paʻi ʻo BAT British American Tobacco i kahi pepa noiʻi i kapa ʻia ʻo "An Experimental Analytical and In Vitro Approach to Bridge Between Different Heated Tobacco Product Variants" ma ka "Contributions to Tobacco & Nicotine Research" puke pai ʻepekema, a alakaʻi i kahi noiʻi ma THP (HNB huahana) Toxicology hoao ana.
I loko o ka hoʻokolohua, ua hoʻohana ʻia nā aerosol a me ka uahi paka o ʻelima mau ʻano o THP a me hoʻokahi THP kumu ma ke ʻano hoʻokolohua, a ua loiloi ʻia ka cytotoxicity e ka viability o nā pūnana epithelial lung kanaka.Ua hōʻike nā hopena i nā hopena cytotoxic a pau i ka hui THP ma kahi o 95% haʻahaʻa ma mua o ka poʻe i loko o ka hui uahi paka, a ʻaʻohe ʻokoʻa nui o ka ʻona ma waena o nā THP ʻano ʻelima a me ka THP kumu.
Wahi a ke aʻo ʻana, ke ulu wikiwiki nei ka hoʻomohala ʻana a me ka hoʻolako ʻana i nā paka a me nā huahana nicotine, ke ʻae nui nei nā mea kūʻai aku i nā huahana hou e like me THP, a ʻo kona palekana a me ka pilikia ma ke ʻano o ka loiloi toxicological pono e nānā i ka ʻoihana.Ke kū wale ka huahana i nā kūlana (me ka hana pākaukau) hiki iā ia ke hoʻokani maikaʻi i kāna kūlana maikaʻi ma ke ʻano he hoʻolālā olakino lehulehu.
Nā kuhikuhi
Ee Tsin Wong, Karsta Luettich, Lydia Cammack, et al.ʻO ka loiloi o ka inhalation o ka uahi paka a me nā aerosol mai nā hui ʻono: 5-pule haʻawina i nā ʻiole A/J.Nūpepa o ka toxicolog i noi ʻia, 2022
Tomasz Jaunky, David Thorne, Andrew Baxter, a me al.ʻO kahi ʻano hoʻokolohua hoʻāʻo a me In Vitro i ke alahaka ma waena o nā ʻano mea like ʻole o ka paka wela.Nā Haʻawina i ka ʻImi Paka a me Nikotini, 2022
Ka manawa hoʻouna: Dec-16-2022
